Bioactive Small Molecules

A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.

Search Within Results

6,811 – 6,825 of 60,533 results

6,811

Creative Biomart Recombinant Protein 377.43 Inquiry Inquiry 10 MG 1/EA

p38 Inhibitor

Pricing & Availability

6,812

Cayman Chemical F2201, Purity: ≥98%, CAS: 1391485-39-4, 10 mg

F2201 is an analog of AM2201 with a fluorine at the 4 position of the naphthyl group. The physiological and toxicological properties of this compound have not been delineated. This product is intended for research and forensic purposes.

Pricing & Availability

6,813

Cayman Chemical CMP8, Purity: ≥98%, CAS: 851107-28-3, 1 mg

A mutant ERα antagonist and ligand used for bump and hole; is selective for ERα containing three substitutions, ErαL384M, ErαM421G, and ErαG521R, over the wild-type ERα and ERβ (IC50s= 29, 1,085, and 2,232 nM, respectively); reduces reporter gene expression in HeLa cells expressing the triple mutant ERα (EC50 = 41 nM).

Pricing & Availability

6,814

Medchemexpress LLC N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)-3-[4-(dimethylamino)but-2-enamido]... | 1604810-84-5 | 98.0% | 5 MG

THZ2 is a potent, selective covalent inhibitor of cyclin-dependent kinase 7 (CDK7) with low-nanomolar inhibitory activity (IC50 ≈ 13.9 nM). It is used in vitro and in vivo to study transcriptional regulation and oncogenic proliferation, particularly in triple-negative breast cancer models.

Potent CDK7 inhibition with IC50 of ~13.9 nM.
Selective activity in the low-nanomolar range for cellular and biochemical assays.
Demonstrated anti-proliferative and pro-apoptotic effects in triple-negative breast cancer models.
Supplied as a solid; soluble in DMSO and available in multiple pack sizes for research use.
Molecular formula C31H28ClN7O2, molecular weight 566.05 g/mol.

Pricing & Availability

6,815

Cayman Chemical Octodrine (hydrochloride), Purity: ≥95%, CAS: 5984-59-8, 5 mg

An analytical reference standard categorized as a stimulant; intended for research and forensic applications

Pricing & Availability

6,816

Cayman Chemical SPA70, Purity: ≥90%, CAS: 931314-31-7, 10 mg

A PXR antagonist (IC50 = 0.51 µM); selective for PXR over 10 additional nuclear receptors at >5 µM, as well as over a panel of 384 kinases at 10 µM; inhibits rifampicin-induced PXR activation from 0.1-10 µM; inhibits rifampicin-induced CYP3A4 activity in primary human hepatocytes; inhibits PXR agonist-induced CYP3A4-mediated metabolism of midazolam and paclitaxel in hPXR-tg mice at 200 mg/kg

Pricing & Availability

6,817

Cayman Chemical 6-Deoxypenciclovir, Purity: ≥95%, CAS: 104227-86-3, 5 mg

An inactive metabolite of famciclovir; a precursor metabolite to penciclovir; has been used in the synthesis of prodrug forms of penciclovir

Pricing & Availability

6,818

Medchemexpress LLC Iso-VQA-ACC acetate | 99.5% | 625.63 | 5 MG

Iso-VQA-ACC acetate is a substrate for constitutive proteasome, typically appearing as a white to off-white solid.

Functions as a substrate for constitutive proteasome
Targets proteasome activity
Involved in the metabolic enzyme/protease pathway
Molecular sequence: iso-Val-Gln-Ala-{ACC}
Achieves a purity of 99.5% by HPLC
Structure confirmed by MS analysis

Pricing & Availability

6,819

eMolecules 522649-59-8 | Medchem Express | Malic enzyme inhibitor ME1 | 1mg | 495800183 | HY-124861 | 351.406 | C20H21N3O3

Medchem Express | Malic enzyme inhibitor ME1 | 1mg | 495800183 | HY-124861 | 522649-59-8 | 351.406 | C20H21N3O3

Pricing & Availability

6,820

Cayman Chemical GBT-440, Purity: ≥98%, CAS: 1446321-46-5, 5 mg

A modulator of sickle hemoglobin; increases HbS affinity for oxygen (EC50s = 8.2 and 415 μM for purified HbS and whole blood from sickle cell anemia patients, respectively); delays oxygen release from and polymerization of HbS in a concentration-dependent manner; increases red blood cell half-life and reduces sickling ex vivo in whole blood isolated from a murine model of sickle cell anemia

Pricing & Availability

6,821

Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 222.24 g/mol | C10H14N4O2 | 5MG

IBMX (3-isobutyl-1-methylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor used as a research reagent and analytical standard. It raises intracellular cyclic AMP and cyclic GMP by inhibiting multiple PDE isoforms and is commonly used in biochemical and cell-based assays. Reported IC50 values reflect activity against several PDE families.

Pricing & Availability

6,822

Medchemexpress LLC EMT inhibitor-2 | 2232228-60-1 | 98.8% | 25 MG

EMT inhibitor-2 (Compound 1) inhibits epithelial-mesenchymal transition (EMT) induced by substances such as IL-1β and TGF-β released from immunocytes. It also inhibits CYP3A4 testosterone and CYP2C9 with IC50s of 49.72 and 5.54 μM, respectively.

Inhibits epithelial-mesenchymal transition (EMT)
Inhibits CYP3A4 testosterone
Inhibits CYP2C9

Pricing & Availability

6,823

Cayman Chemical Darusentan, Purity: ≥98%, CAS: 171714-84-4, 1 mg

An ETA receptor antagonist (Ki = 13 nM in rat aortic vascular smooth muscle cells); inhibits ET-1-induced contractions in isolated rat aortic rings and mesenteric microvessels (pA2s = 8.1 and 7.97, respectively); decreases systolic blood pressure in DOCA-salt hypertensive rats at 50 mg/kg; decreases MAP and LVDP in normotensive pigs at 1 and 5 mg/kg; reduces myocardial infarct size as a percentage of the area at risk in a porcine model of LAD coronary artery ligation-induced ischemia-reperfusion injury

Pricing & Availability

6,824

Cayman Chemical 4-Methyl-7-(4-nitrophenoxy)-2H-chromen-2-one, Purity: ≥98%, CAS: 1644277-00-8, 5 mg

A fluorescent coumarin derivative; ex/em = 323/445 nm, respectively

Pricing & Availability

6,825

Cayman Chemical Cypermethrin-d9, Purity: ≥99% deuterated forms (d1-d9), 5 mg

An internal standard for the quantification of cypermethrin by GC- or LC-MS

Pricing & Availability

Bioactive Small Molecules

Filtered Search Results

Narrow Results

Creative Biomart Recombinant Protein 377.43 Inquiry Inquiry 10 MG 1/EA Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)-3-[4-(dimethylamino)but-2-enamido]... | 1604810-84-5 | 98.0% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Iso-VQA-ACC acetate | 99.5% | 625.63 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 222.24 g/mol | C10H14N4O2 | 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC EMT inhibitor-2 | 2232228-60-1 | 98.8% | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Creative Biomart Recombinant Protein 377.43 Inquiry Inquiry 10 MG 1/EA

Medchemexpress LLC N-(3-{[5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)-3-[4-(dimethylamino)but-2-enamido]... | 1604810-84-5 | 98.0% | 5 MG

Medchemexpress LLC Iso-VQA-ACC acetate | 99.5% | 625.63 | 5 MG

Medchemexpress LLC 3-isobutyl-1-methylxanthine | 28822-58-4 | MFCD00005584 | 222.24 g/mol | C10H14N4O2 | 5MG

Medchemexpress LLC EMT inhibitor-2 | 2232228-60-1 | 98.8% | 25 MG